Although drug analysis using immunological methods is fast, it is not always reliable. The available screening tests can easily lead to false positive results. For the confirmation of such immunoassay results,
complex and time-consuming GC-MS analysis has been so far performed by the Stuttgart hospital.
Since March 2017, the Toxtyper® system has been used for the screening of drugs and toxins in blood, oral fluid and urine. Without time-consuming sample preparation, Toxtyper® delivers fast and reliable results that are highly specific and reproducible. In addtion, the Toxtyper® also provides a high degree of safety in toxicological analysis prior to the neurological diagnosis of irreversible brain failure.
A 34 year old patient with dizziness, nausea and vomiting is admitted to the emergency room.From the anamnesis there is a suspicion of drug consumption, however the patient denies the use of illegal drugs. Urine screening using various immunoassays was negative for Amphetamines, Barbiturates, Benzodiapezepins, Cocaine, Opiates and Cannabis. The Toxtyper® identified Mitragynin and several metabolites of Paynanthein and Speciociliantin, which are alkaloids present in leaves and fruits of the Kratom tree. Kratom is used for substitution of Opioids and is not regulated by the German narcotics law.